Article

<i>Etv6/Runx1</i> Fusion Gene Abrogation Decreases The Oncogenic Potencial Of Tumour Cells In A Preclinical Model Of Acute Lymphoblastic Leukaemia

2019-10-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The t(12;21)(p13;q22), which fuses ETV6 and RUNX1 genes, is the most common genetic abnormality in children with B-cell precursor acute lymphoblastic leukaemia. The implication of the fusion protein in leukaemogenesis seems to be clear. However, its role in the maintenance of the disease continues to be controversial. <h4>Aim</h4> To eliminate the expression of the ETV6...

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Literature Corpus work: cefdc1be-3103-5778-9097-5347b343e893
DOI: 10.1101/809525

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<i>Etv6/Runx1</i> Fusion Gene Abrogation Decreases The Oncogenic Potencial Of Tumour Cells In A Preclinical Model Of Acute Lymphoblastic LeukaemiaDOI 10.1101/809525Read

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