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Article

Development of an Isoform-Discriminating RT-qPCR Assay for Transcript-Level Profiling of Human ASAH2 in Colorectal Cancer Cell Models

2026-05-22

Abstract excerpt

<title>Abstract</title> <p> <italic>N-Acylsphingosine Amidohydrolase 2 (ASAH2)</italic> encodes neutral ceramidase (nCDase), one of several ceramidases involved in sphingolipid metabolism, that hydrolyzes ceramide into sphingosine and contributes to regulation of the ceramide–sphingosine-1-phosphate signaling axis. Compared with acid and alkaline ceramidases, nCDase remains less well characterized, and the expr...

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Literature Corpus work
ceeb4402-0333-5761-baad-a49a3aa91b86
DOI
10.21203/rs.3.rs-9690223/v1
Open publication

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Development of an Isoform-Discriminating RT-qPCR Assay for Transcript-Level Profiling of Human ASAH2 in Colorectal Cancer Cell ModelsDOI 10.21203/rs.3.rs-9690223/v1
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