Article

Modeling Familial MASH by iPSC-Hepatocytes

2025-11-22

Abstract excerpt

Increasing obesity has led to a vast rise in metabolic dysfunction-associated steatotic liver disease (MASLD) in the general population with a significant fraction progressing to metabolic dysfunction-associated steatohepatitis (MASH). Patients with MASH progressively develop inflammation and fibrosis that over time can develop into cirrhosis with an increased risk for hepatocellular carcinoma. Despite the study o...

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Literature Corpus work: ceb55fef-fdf8-552e-8c7e-11b1c1eabae5
DOI: 10.1101/2025.11.18.25338158

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