Article

Predicting Metabolic Dysfunction Associated Steatotic Liver Disease Risk Using Patient-Derived Induced Pluripotent Stem Cells

2025-01-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) is reversible at early stages, making early identification of high-risk individuals clinically valuable. Previously, we demonstrated that patient-derived induced pluripotent stem cells (iPSCs) harboring MASLD DNA risk variants exhibit greater oleate-induced intracellular lipid accumulation than those w...

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Literature Corpus work: 0ec7f78a-9ab5-53b5-b7ff-a372b56916bd
DOI: 10.1101/2025.01.13.632567

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