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Article

Developmental modeling of hepatogenesis using obese iPSCs-hepatocyte differentiation uncovers pathological features

1 Aug 2022

Abstract excerpt

Obesity is a multigene disorder. However, in addition to genetic factors, environmental determinants also participate in developing obesity and related pathologies. Thus, obesity could be best described as a combination of genetic and environmental perturbations often having its origin during the early developmental period. Environmental factors such as energy-dense food and sedentary lifestyle are known to be...

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PMID: 35915082
DOI: 10.1038/s41419-022-05125-9

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