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Article

Deciphering the age-dependent changes of pulmonary fibroblasts in mice by single-cell transcriptomics

29 Nov 2023

Abstract excerpt

Background and objectives: The heterogeneity of pulmonary fibroblasts, a critical aspect of both murine and human models under physiological and pathological conditions, is well-documented. Yet, consensus remains elusive on the subtypes, lineage, biological attributes, signal transduction pathways, and plasticity of these fibroblasts. This ambiguity significantly impedes our understanding of the fibrotic...

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PMID: 38094618
DOI: 10.3389/fcell.2023.1287133

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