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Article

Influence of age on wound healing and fibrosis

1 Nov 2012

Abstract excerpt

The incidence and severity of fibrotic lung diseases increase with age, but very little is known about how age-related changes affect the mechanisms that underlie disease emergence and progression. Normal ageing includes accumulation of DNA mutations, oxidative and cell stresses, mitochondria dysfunction, increased susceptibility to apoptosis, telomere length dysfunction and differential gene expression as a...

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PMID: 23124998
DOI: 10.1002/path.4122

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