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Lung Fibroblasts, Aging, and Idiopathic Pulmonary Fibrosis

1 Dec 2016

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is an aging-associated, progressive, and irreversible lung disease of unknown etiology, elusive pathogenesis, and very limited therapeutic options. The hallmarks of IPF are aberrant activation of alveolar epithelial cells and accumulation of fibroblasts and myofibroblasts along with excessive production of extracellular matrix. The linkage of aging with this disorder is...

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PMID: 28005427
DOI: 10.1513/annalsats.201605-341aw

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