Article

Primary cilia regulate mechanical adaptation of tendon and enthesis via hedgehog signaling

2026-04-29

Abstract excerpt

<h4>Background</h4> Physical loading mediates postnatal growth, homeostasis, and healing of the tendon and its attachment to bone, which is critical for rotator cuff functional integrity. Our prior studies have highlighted the mechano-sensing role of primary cilia; However, the mechanisms through which cilia convert mechanical stimuli into structural functional adaptation under altered loading conditions remain u...

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Literature Corpus work: ce87209e-7412-5221-97fb-98732483a78e
DOI: 10.64898/2026.04.25.720837

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