Back to search

Article

Multi-omic characterization of MAP4 in pancreatic adenocarcinoma progression: epitranscriptomic networks, EMT Activation, and stromal-immune dynamics

2025-05-21

Abstract excerpt

<title>Abstract</title> <p>Background Pancreatic adenocarcinoma (PAAD), particularly pancreatic ductal adenocarcinoma (PDAC), is a lethal malignancy with limited therapeutic advancements. Microtubule-associated protein 4 (MAP4), implicated in tumor progression in other cancers, has not been systematically explored in PAAD. This study aims to investigate the role of MAP4 in the progression of PAAD, its associatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ce795093-d535-5eee-8c39-775f8b6f355c
DOI
10.21203/rs.3.rs-6702603/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Multi-omic characterization of MAP4 in pancreatic adenocarcinoma progression: epitranscriptomic networks, EMT Activation, and stromal-immune dynamicsDOI 10.21203/rs.3.rs-6702603/v1
Single-cell and spatially resolved atlas of pancreatic cancer reveals immunophenotypes associated with clinical outcomeSemantic proximity
Integrating multi-modal transcriptomics identifies cellular subtypes with distinct roles in PDAC progressionSemantic proximity
Single cell RNA-seq reveals the CCL5/SDC1 receptor-ligand interaction between T cells and tumor cells in pancreatic cancerSemantic proximity
Integrating multi-modal transcriptomics identifies cellular subtypes with distinct roles in PDAC progressionSemantic proximity
Evolution of the Spatial transcriptomic landscape during the progression of high-grade pancreatic intraductal papillary mucinous neoplasms to invasive cancerSemantic proximity
Integrated transcriptional analysis reveals macrophage heterogeneity and tumor-macrophage interactions in the progression of pancreatic ductal adenocarcinomaSemantic proximity
Comprehensive Analysis of Clinical Prognosis and Molecular Immune Characterization of TPM4 in Pancreatic CancerSemantic proximity
Comprehensive characterization of extracellular matrix-related genes in PAAD identified a novel prognostic panel related to clinical outcomes and immune microenvironment: A silico analysis with in vivo and vitro validationSemantic proximity
Single-cell transcriptome analysis reveals subtype-specific clonal evolution and microenvironmental changes in liver metastasis of pancreatic adenocarcinoma and their clinical implicationsSemantic proximity
Coordinated single-cell tumor microenvironment dynamics reinforce pancreatic cancer subtypeSemantic proximity
Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreasSemantic proximity
Heterogeneous tumor microenvironment in pancreatic ductal adenocarcinoma: An emerging role of single‐cell analysisSemantic proximity
Select a neighboring publication to make it the new centre.