Article

An Unbiased Proteomic Platform for ATE1-based Arginylation Profiling

2024-06-02

Abstract excerpt

Protein arginylation is an essential posttranslational modification (PTM) catalyzed by arginyl-tRNA-protein transferase 1 (ATE1) in mammalian systems. Arginylation features a post-translational conjugation of an arginyl to a protein, making it extremely challenging to differentiate from translational arginine residues with the same mass in a protein sequence. Here we present a general ATE1-based arginylation profi...

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Literature Corpus work: ce6d9d00-0a9c-5294-b5d1-26391937ea8f
DOI: 10.1101/2024.06.01.596974

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