Article
Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap.
Molecular & cellular proteomics : MCP - 1 Aug 2014
Trentini Débora Broch, Fuhrmann Jakob, Mechtler Karl, Clausen Tim
Abstract excerpt
Arginine phosphorylation is an emerging post-translational protein modification implicated in the bacterial stress response. Although early reports suggested that arginine phosphorylation also occurs in higher eukaryotes, its overall prevalence was never studied using modern mass spectrometry methods, owing to technical difficulties arising from the acid lability of phosphoarginine. As shown recently, the McsB...
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