Article

Aberrant Local Synchrony in Distinct Mouse Models of Epileptic Encephalopathy

2023-10-27

Abstract excerpt

Identifying and quantifying synchronous activity of primary neuronal networks using multielectrode arrays (MEAs) can potentially provide a medium-throughput platform to screen potential therapeutics for genetic epileptic encephalopathies (EEs). However, successfully identifying screenable synchrony phenotypes in vitro poses significant experimental and analytical challenges. Primary neuronal cultures quickly beco...

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Literature Corpus work: ce517c4b-6e94-5062-bf7b-723f7a98db7f
DOI: 10.1101/2023.10.24.563817

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