Article

Nested oscillatory dynamics in cortical organoids model early human brain network development

2018-06-29

Abstract excerpt

<h4>SUMMARY</h4> Structural and transcriptional changes during early brain maturation follow fixed developmental programs defined by genetics. However, whether this is true for functional network activity remains unknown, primarily due to experimental inaccessibility of the initial stages of the living human brain. Here, we developed cortical organoids that spontaneously display periodic and regular oscillatory n...

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Literature Corpus work: 7815a523-9f3f-57f4-a39e-fbd0afa2ff7f
DOI: 10.1101/358622

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