Article

A sex-specific evolutionary interaction between <i>ADCY9</i> and <i>CETP</i>

2021-05-14

Abstract excerpt

Pharmacogenomic studies have revealed associations between rs1967309 in the adenylyl cyclase type 9 ( ADCY9 ) gene and clinical responses to the cholesteryl ester transfer protein (CETP) modulator dalcetrapib, however, the mechanism behind this interaction is still unknown. Here, we characterized selective signals at the locus associated with the pharmacogenomic response in human populations and we show that rs19...

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Literature Corpus work: ce4f4191-b92b-5508-ab5f-9d9cca3b7047
DOI: 10.1101/2021.05.12.443794

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