Article

STAG3 promotes exit from pluripotency through post-transcriptional mRNA regulation in the cytoplasm

2024-05-31

Abstract excerpt

<h4>ABSTRACT</h4> STAG proteins are key regulators of the cohesin complex and are often linked to alterations in cell identity and disease. Among the mammalian STAG paralogs, STAG3 has been less extensively studied beyond its known roles in meiosis. In this work, we demonstrate that STAG3 is expressed in mouse embryonic stem cells (mESCs) and primordial germ cell-like cells (PGCLCs), where it is required for cell...

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Literature Corpus work: ce2a260d-8fa4-50c1-8698-a7a2b8e6a95e
DOI: 10.1101/2024.05.31.595485

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