Article

Estimating disease heritability from complex pedigrees allowing for ascertainment and covariates

2023-07-13

Abstract excerpt

We propose TetraHer, a method for estimating the liability heritability of binary phenotypes. TetraHer has five key features. Firstly, it can be applied to data from complex pedigrees, that contain multiple types of relationships. Secondly, it can correct for ascertainment of cases or controls. Thirdly, it can accommodate covariates. Fourthly, it can model the contribution of common environment. Fifthly, it produc...

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Literature Corpus work: ce25eb1f-1328-5463-a6f2-a18838dd5793
DOI: 10.1101/2023.07.13.23292588

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