Article

Liability-scale heritability estimation for biobank studies of low prevalence disease

2022-02-04

Abstract excerpt

Theory for liability-scale models of the underlying genetic basis of complex disease provides an important way to interpret, compare and understand results generated from biological studies. In particular, liability models facilitate an understanding and comparison of the relative importance of genetic and environmental risk factors that shape different clinically important disease outcomes, through estimation of...

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Literature Corpus work: 587ebb8e-8392-5822-a56a-a497c1c25fcb
DOI: 10.1101/2022.02.02.22270229

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