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Surface display of an Anti-CD3 scFv by Saccharomyces boulardii attenuates DSS-induced colitis in mice

2026-06-24

Abstract excerpt

<title>Abstract</title> <p> <italic>Saccharomyces boulardii</italic> (Sb) is a probiotic yeast amenable to genetic manipulation, making it a promising platform for delivering recombinant biotherapeutics to the intestinal lumen. In this study, we engineered a recombinant Sb strain to display an anti-CD3 single-chain variable fragment (scFv) on its surface and evaluated its potential as an oral antibody delivery...

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Literature Corpus work
ce165056-6906-5a57-99f8-86ce6a693619
DOI
10.21203/rs.3.rs-9997807/v1
Open publication

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Surface display of an Anti-CD3 scFv by Saccharomyces boulardii attenuates DSS-induced colitis in miceDOI 10.21203/rs.3.rs-9997807/v1
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