Article

Wave propagation enhances extracellular signal strength in small excitable tissues

2025-07-10

Abstract excerpt

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) offer new opportunities to study cardiac dynamics and drug responses. High-throughput platforms often rely on extracellular potential (EP) recordings as a proxy for transmembrane voltage, making EP signal strength critical for analysis. EPs arise from spatial inhomogeneities – either intrinsic or induced by wave propagation. Using a computation...

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Literature Corpus work: cdf6ac2f-883f-56ee-b81f-84687998db3c
DOI: 10.1101/2025.07.07.663416

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