Article

Field potential Imaging in human iPSC- derived Cardiomyocytes using UHD-CMOS-MEA

2025-04-04

Abstract excerpt

Evaluation using beat propagation analysis of human iPS cardiomyocytes is an effective approach for assessing human cardiac safety in drug development. However, current applications are primarily focused on detecting QT prolongation and arrhythmia risk, while its ability to comprehensively detect cardiotoxicity remains insufficient. Additionally, predicting the mechanism of action, which is crucial in drug develop...

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Literature Corpus work: 1f149504-37fb-5647-a348-6d19b5163f3e
DOI: 10.1101/2025.03.31.646249

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