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Piperine Enhances Mitochondrial Biogenesis to Mitigate Stress in SH ‐ SY5Y Neuroblastoma Cells

1 Jul 2025

Abstract excerpt

ABSTRACT Mitochondrial dysfunction plays a crucial role in neurodegenerative disorders. Enhancing mitochondrial biogenesis is a promising therapeutic strategy for mitigating mitochondrial damage. Piperine, a bioactive alkaloid from black pepper, the fruit of Piper nigrum L. in the family Piperaceae, has demonstrated neuroprotective effects against mitochondrial stress. However, its effects on mitochondrial health...

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PMID: 40678336
DOI: 10.1002/fsn3.70637

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