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Assessing Neuroprotective Effects of Mitoquinone on H2O2-Induced Neurotoxicity in SH-SY5Y Neuroblastoma Cells

2024-03-06

Abstract excerpt

<title>Abstract</title> <p>Oxidative stress, a major player in secondary brain injury, has been shown to contribute to apoptosis, neuroinflammation, and mitochondrial dysfunction. The possibility of targeting the Nrf2-Keap-ARE pathway, using mitochondria-targeted antioxidants, such as mitoquinone (MitoQ), has been proposed to treat neurotoxicity. The neuroprotective effects of MitoQ on human neuroblastoma SH-SY5Y...

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Literature Corpus work
853f4f7f-b3e7-52f6-8b59-d7b8844d2efc
DOI
10.21203/rs.3.rs-3995257/v1
Open publication

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