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Automated image segmentation uncovers the role of CD74 high human microglia in cognitive decline

2025-10-29

Abstract excerpt

<title>Abstract</title> <p> The role of activated microglia in Alzheimer’s disease (AD) is well established; the proportion of stage III activated microglia has been associated with AD and cognitive decline, but this morphologically defined subtype is relatively uncommon (1-2% of microglia) and its cellular function is unknown. Single-cell RNA-sequencing revealed CD74 as a marker gene that is enriched in immunol...

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Literature Corpus work
cdceb8d5-13b9-5244-8c5e-f9b75eff5ee6
DOI
10.21203/rs.3.rs-7851255/v1
Open publication

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Automated image segmentation uncovers the role of CD74 high human microglia in cognitive declineDOI 10.21203/rs.3.rs-7851255/v1
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