Article

Neuronal and astrocytic adaptations in the lateral habenula during withdrawal from chronic ethanol

2026-08-10

Abstract excerpt

The lateral habenula (LHb) encodes aversive states and negative affect, positioning it as a candidate region for the negative reinforcement that drives alcohol withdrawal. However, little is known about how chronic ethanol exposure affects LHb neuronal function and glial biology during withdrawal. Here, we used chronic intermittent ethanol (CIE) vapor exposure, a well-established model of alcohol dependence that r...

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Literature Corpus work: cdc085ed-5091-509f-b79c-ac35b3a30016
DOI: 10.64898/2026.08.04.742855

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