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Article

Impaired Synaptic Activity in the Basolateral Amygdala Is Associated With an Alcohol Use Disorder-Like Vulnerable Phenotype in Male Rats.

Addiction biology - 1 Oct 2025

Cadeddu Davide, Lucente Erika, Ericson Mia, Söderpalm Bo, Adermark Louise, Domi Ana

Abstract excerpt

Alcohol use disorder (AUD) is associated with a loss of control over alcohol use, putatively driven by maladaptive changes in neural circuitries, including the basolateral amygdala (BLA). The BLA, known for its role in emotional regulation and associative learning, contributes to the reinforcement of alcohol-related behaviours, making it a critical target for understanding the underlying mechanisms of...

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PMID: 41085474
DOI: 10.1111/adb.70091
PMCID: PMC12519881

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