Article

Association of rare<i>APOE</i>missense variants with Alzheimer's disease in the Japanese population

2024-11-06

Abstract excerpt

<h4>Background: </h4> APOE is a major susceptibility gene for Alzheimer's disease (AD). Recent studies in Europe and the US have identified rare missense variants (RMVs) in APOE which are significantly associated with AD. However, little is known regarding APOE RMVs in East Asians, including the Japanese, and their association with AD and lipid metabolism. <h4>Objective: </h4> To identify APOE RMVs in the Japanese...

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Literature Corpus work: cdbd30fc-0fdb-5d61-9522-0ba025ef79d9
DOI: 10.1101/2024.11.05.24316515

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