Article

Structural variation, selection, and diversification of the <i>NPIP</i> gene family from the human pangenome

2025-02-05

Abstract excerpt

<h4>ABSTRACT</h4> The NPIP (nuclear pore interacting protein) gene family has expanded to high copy number in humans and African apes where it has been subject to an excess of amino acid replacement consistent with positive selection (1). Due to the limitations of short-read sequencing, NPIP human genetic diversity has been poorly understood. Using highly accurate assemblies generated from long-read sequencing...

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Literature Corpus work: 085224a0-7b6f-511d-be18-61dcdf3a9b4e
DOI: 10.1101/2025.02.04.636496

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