Article

Plasma proteome signatures in sickle cell anaemia and effect of hydroxyurea treatment

2026-02-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Sickle Cell Anaemia (SCA), a genetic blood disorder caused by a single mutation in the beta globin gene, displays a highly variable clinical course. Hydroxyurea (HU), an effective treatment, has an unclear mechanism of action. Plasma proteins can act as biomarkers for understanding disease states and response to HU treatment in SCA patients. <h4>Methods</h4> Plasma proteome...

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Literature Corpus work: cd6ad1cb-af08-5f3a-93fe-7bc494b733c0
DOI: 10.64898/2026.02.08.26345875

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