Plasma proteome profiling combined with clinical and genetic features reveals the pathophysiological characteristics of β-thalassemia

Abstract excerpt

The phenotype of β-thalassemia underlies multigene interactions, making clinical stratification complicated. An increasing number of genetic modifiers affecting the disease severity have been identified, but are still unable to meet the demand of precision diagnosis. Here, we systematically conducted a comparative plasma proteomic profiling on patients with β-thalassemia and healthy controls. Among 246...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blood groups and transfusion
• Share to Hemoglobinopathies and Related Disorders
• Share to Iron Metabolism and Disorders