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Proteogenomic analysis of 5,411 plasma proteins in sickle cell disease patients

2026-04-07

Abstract excerpt

<h4>ABSTRACT</h4> There are few therapeutic options to treat patients with sickle cell disease (SCD), a blood disorder caused by mutations in the β-globin gene that affects >7M individuals worldwide. Combining human genetics and high-throughput proteomics can help identify new drug targets. Here, we present results from a proteogenomic analysis of the plasma proteome in SCD patients. We measured the levels of 5,4...

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Literature Corpus work
bb0b4738-5ab1-520d-a3be-4a6d9b8c0822
DOI
10.64898/2026.04.06.26350255
Open publication

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Proteogenomic analysis of 5,411 plasma proteins in sickle cell disease patientsDOI 10.64898/2026.04.06.26350255
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