Leveraging Multi-Omics Approaches and Advanced Technologies to Unravel the Molecular Complexities, Modifiers, and Precision Medicine Strategies for Hemoglobin H Disease.

Abstract excerpt

Hemoglobin H (HbH) disease, a form of alpha-thalassemia, poses significant clinical challenges due to its complex molecular underpinnings. It is characterized by reduced synthesis of the alpha-globin chain. The integration of multi-omics and precision medicine holds immense potential to comprehensively understand and capture interactions at the molecular and genetic levels. This review integrates current...

Topics

• Humans
• Precision Medicine
• Genomics
• alpha-Thalassemia
• Proteomics
• Metabolomics
• Computational Biology
• Disease Management
• Gene Editing
• Biomarkers
• Genetic Predisposition to Disease