Article

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell type set

2020-06-25

Abstract excerpt

How have complex brains evolved from simple circuits? Here we investigated brain region evolution at cell type resolution in the cerebellar nuclei (CN), the output structures of the cerebellum. Using single-nucleus RNA sequencing in mice, chickens, and humans, as well as STARmap spatial transcriptomic analysis and whole-CNS projection tracing in mice, we identified a conserved cell type set containing two classes...

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Literature Corpus work: 27e91b0a-abb3-56ba-8d2c-8c7d78b89d8f
DOI: 10.1101/2020.06.25.170118

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