Article

mTORC1 Activation In Presumed Classical Monocytes: Observed Correlates With Human Size Variation and Neuropsychiatric Disease

2024-02-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Gain of function disturbances in nutrient sensing are likely the largest component in human age-related disease. Mammalian target of rapamycin complex 1 (mTORC1) activity affects health span and longevity. The drugs ketamine and rapamycin are effective against chronic pain and depression, and both affect mTORC1 activity. Our objective was to measure phosphorylated p70S6K, a...

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Literature Corpus work: cd518d3f-bdfb-55c4-90bb-8fc513236af2
DOI: 10.1101/2024.01.31.578140

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