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Article

Safety and efficacy of rapamycin on healthspan metrics after one year: PEARL Trial Results

2024-08-22

Abstract excerpt

<h4>Background</h4> Low-dose rapamycin promotes longevity in mice, but clinical safety and longevity data effects in humans remain limited. <h4>Objectives</h4> Evaluate the long-term safety of intermittent low-dose rapamycin in a healthy, normative-aging human cohort. <h4>Design</h4> This decentralized double-blinded, randomized, placebo-controlled trial ( NCT04488601 , registered 2020-07-28) was performed over 48...

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Literature Corpus work
a8189c29-07e3-55fb-a693-7b0236a5238c
DOI
10.1101/2024.08.21.24312372
Open publication

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Safety and efficacy of rapamycin on healthspan metrics after one year: PEARL Trial ResultsDOI 10.1101/2024.08.21.24312372
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