Article

Magnesium and Rapamycin in Long Covid and Longevity: Mechanistic (Part A) and Therapeutic (Part B) Proposals

2026-08-03

Abstract excerpt

A global shortfall in magnesium (Mg) is linked to long Covid and a shortened lifespan. The mTOR (mammalian or mechanistic target of rapamycin)/AMPK (AMP-activated protein kinase) ratio increases with age and these kinases are inversely related. A balanced mTOR:AMPK ratio, promoted by rapamycin (RAP), is linked to healthy aging. mTOR is anabolic and AMPK is catabolic. Mg and RAP are synergistic collaborators in sup...

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Literature Corpus work: e3569938-d65a-5c37-ba8a-2f522c8ca55e
DOI: 10.32388/u5jtwn.3

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