Back to search

Article

Transdermal Delivery of Ultradeformable Cationic Liposomes Complexed with miR211-5p (UCL-211) Stabilizes BRAFV600E+ Melanocytic Nevi

2024-10-21

Abstract excerpt

Small non-coding RNAs (e.g. siRNA, miRNA) are involved in a variety of melanocyte-associated skin conditions and act as drivers for alterations in gene expression within melanocytes. These molecular changes can potentially affect the cellular stability of melanocytes and promote their oncogenic transformation. Thus, small RNAs can be considered as therapeutic targets for these conditions, however, their topical de...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cd0910a9-ee91-5376-9c15-23730594c094
DOI
10.1101/2024.10.17.618694
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transdermal Delivery of Ultradeformable Cationic Liposomes Complexed with miR211-5p (UCL-211) Stabilizes BRAFV600E+ Melanocytic NeviDOI 10.1101/2024.10.17.618694
A comprehensive review of the medical and cosmetic applications of exosomes in dermatologySemantic proximity
In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metastatic Melanoma.Semantic proximity
Mimicking Melanosomes: Polydopamine Nanoparticles as Artificial MicroparasolsSemantic proximity
Anti‐melanogenic effect of exosomes derived from human dermal fibroblasts (BJ‐5ta‐Ex) in C57BL/6 mice and B16F10 melanoma cellsSemantic proximity
Tetrahedral DNA‐Based Functional MicroRNA‐21 Delivery System: Application to Corneal Epithelial Wound HealingSemantic proximity
Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.Semantic proximity
Synthesis of ionizable lipopolymers using split-Ugi reaction for pulmonary delivery of various size RNAs and gene editingSemantic proximity
Biomimetic Melanosomes Promote Orientation-Selective Delivery and Melanocyte Pigmentation in the H2O2‑Induced Vitiligo Mouse ModelSemantic proximity
Development of Skin Diseases Treatment based on Exosome Derived from Plants, Humans, Medicinal Algae and FungiSemantic proximity
Microneedle-assisted genome editing: A transdermal strategy of targeting NLRP3 by CRISPR-Cas9 for synergistic therapy of inflammatory skin disordersSemantic proximity
Engineered virus-like particle-assembled VEGF-targeting Cas9 ribonucleoprotein treatment alleviates neovascularization in wet age-related macular degenerationSemantic proximity
Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis ConditionsSemantic proximity
Select a neighboring publication to make it the new centre.