Article

Unbiased association and expression studies identify novel genes for tooth development

2017-10-26

Abstract excerpt

Previously reported co-occurrence of colorectal cancer (CRC) and tooth agenesis (TA) and the overlap in disease-associated gene variants suggest involvement of similar molecular pathways. In this study, we took an unbiased approach and tested genome-wide significant CRC-associated variants for association with isolated TA. Thirty single nucleotide variants (SNVs) in CRC-predisposing genes/loci were genotyped in a...

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Literature Corpus work: ccc67481-1217-58f5-909d-e078b0657644
DOI: 10.1101/209684

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