Article

Whole Exome Sequencing Uncovers Key Genetic Variants in Congenital Tooth Agenesis: An Integrative Omics Approach

2024-11-27

Abstract excerpt

This study investigates the genetic underpinnings of congenital tooth agenesis (CTA) using a multiomics approach, integrating whole exome sequencing (WES) and RNA expression analysis. WES was used to analyze the genetic basis of CTA in six affected individuals one with syndromic and five with non-syndromic CTA alongside three healthy and two internal controls. We identified both known and novel variants in candida...

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Literature Corpus work: 43a4b367-8fb3-5f70-a8a9-5f052b16cbc7
DOI: 10.1101/2024.11.26.24317461

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