Article

Understanding Tooth Agenesis: A Multi-omics Insight into MicroRNA Regulation

2024-09-03

Abstract excerpt

This study reveals novel microRNAs (miRNAs) implicated in congenital tooth agenesis (CTA), a common dental anomaly with a complex genetic basis. Through a multi-omics approach combining bioinformatics, whole exome sequencing, metabolite analysis, and gene expression profiling, we identified eight key miRNAs potentially involved in tooth development. Among these, four miRNAs viz. miR-218-5p, miR-15b-5p, miR-200b-3p...

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Literature Corpus work: 9b281e14-c344-518a-87f2-5df32d549e0a
DOI: 10.1101/2024.09.02.24312916

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