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Intrinsic IL-6 expression reduces rhIL-6-induced JAK/STAT activation and promotes glucose and oleic acid oxidation in cultured human myoblasts

2026-05-07

Abstract excerpt

<h4>ABSTRACT</h4> Interleukin-6 (IL-6), produced by skeletal muscle and extramuscular tissues, regulates skeletal muscle function through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. However, the interaction between intrinsic (locally produced) IL-6 and extrinsic (circulating) IL-6 in skeletal muscle remains unclear. We investigated whether and how intrinsic expression of...

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Literature Corpus work
ccbf2343-db30-5324-940b-ea7f36bbbec6
DOI
10.64898/2026.05.06.722928
Open publication

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Intrinsic IL-6 expression reduces rhIL-6-induced JAK/STAT activation and promotes glucose and oleic acid oxidation in cultured human myoblastsDOI 10.64898/2026.05.06.722928
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