Article
Interleukin-6: From molecular mechanisms of signal transduction to physiological properties and therapeutic targeting
2015-11-01
Abstract excerpt
Interleukin-6 (IL-6) is one of the most important proinflammatory cytokines that has a broad spectrum of immunoregulatory properties. The molecular mechanisms of signal transduction of IL-6 and its receptor, which have been previously established, were later supplemented with a concept of trans-signaling. The selective inhibition of this signaling cascade would allow the modulation of the pathological effects of I...
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Identifiers and source
- Literature Corpus work
- def52a41-7b02-560c-924b-f78b83dcca6a
- DOI
- 10.1134/s0026893315060060