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Article

Interleukin-6-dependent phenotypic modulation of cardiac fibroblasts after acute myocardial infarction.

Basic research in cardiology - 1 Jan 2014

Müller Julia, Gorressen Simone, Grandoch Maria, Feldmann Kathrin, Kretschmer Inga, Lehr Stefan, Ding Zhaoping, Schmitt Joachim P, Schrader Jürgen, Garbers Christoph, Heusch Gerd, Kelm Malte, Scheller Jürgen, Fischer Jens W

Abstract excerpt

Interleukin-6 (IL-6) is a multifunctional cytokine that orchestrates the immune response to a wide variety of pathophysiologic challenges but also contributes to tissue homeostasis. Furthermore, IL-6 is elevated in patients with acute myocardial infarction. Hyaluronan (HA) is an extracellular carbohydrate that has been implicated in wound healing and accumulates after acute myocardial infarction (AMI). Aim of...

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Identifiers

PMID: 25236954
DOI: 10.1007/s00395-014-0440-y

Genes

CCL5
HAS1
STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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