Protein 4.2: a complex linker.

doi:10.1016/j.bcmd.2009.01.005

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Article

Protein 4.2: a complex linker.

Blood cells, molecules & diseases - 1 Jan 2000

Satchwell Timothy J, Shoemark Debbie K, Sessions Richard B, Toye Ashley M

Abstract excerpt

The peripheral membrane protein, protein 4.2, is one of the most abundant protein components of the erythrocyte membrane. Protein 4.2 has an important role in red cell membrane structure, its absence due to natural mutations in humans or gene knockout in mice has a detrimental effect on membrane stability and results in hereditary spherocytosis. It is known to be a point of connection between the band 3 complex...

Topics

Amino Acid Sequence
Animals
Blood Proteins
CD47 Antigen
Cell Shape
Cell Survival
Cytoskeletal Proteins
Cytoskeleton
Erythrocyte Membrane
Humans
Membrane Proteins
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Knockout

Models, Molecular

Molecular Sequence Data

Mutation

Phosphorylation

Protein Conformation

Source

Open in PubMed

Identifiers

PMID: 19269200
DOI: 10.1016/j.bcmd.2009.01.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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