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Article

The cytoskeletal binding domain of band 3 is required for multiprotein complex formation and retention during erythropoiesis.

Haematologica - 1 Jan 2015

Satchwell Timothy J, Hawley Bethan R, Bell Amanda J, Ribeiro M Leticia, Toye Ashley M

Abstract excerpt

Band 3 is the most abundant protein in the erythrocyte membrane and forms the core of a major multiprotein complex. The absence of band 3 in human erythrocytes has only been reported once, in the homozygous band 3 Coimbra patient. We used in vitro culture of erythroblasts derived from this patient, and separately short hairpin RNA-mediated depletion of band 3, to investigate the development of a band 3-deficient...

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Identifiers

PMID: 25344524
DOI: 10.3324/haematol.2014.114538
PMCID: PMC4281326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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