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Molecular interaction between steroid sulfatases and formylglycine generating enzyme: A computational study with multiple mutations

2022-08-12

Abstract excerpt

Major naturally occurring estrogens are estrone, estradiol and estratriol. Sulfates of naturally occurring estrogen act as reservoirs of potent estrogen and are important at different stages of life among which estrone sulfate is found to be circulating ten times more than estradiol specifically in postmenopausal women. Sulfate esters of estrogen are hydrolyzed by steroid sulfatases (STS) only after it is activate...

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Literature Corpus work
cc7f26aa-a038-5ee5-a2ae-04f41836f674
DOI
10.21203/rs.3.rs-1931556/v1
Open publication

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Molecular interaction between steroid sulfatases and formylglycine generating enzyme: A computational study with multiple mutationsDOI 10.21203/rs.3.rs-1931556/v1
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