Article
The dimerization motif of cytosolic sulfotransferases.
FEBS letters - 9 Feb 2001
Petrotchenko E V, Pedersen L C, Borchers C H, Tomer K B, Negishi M
Abstract excerpt
Cytosolic sulfotransferases sulfate steroids such as estrogens and hydroxysteroids. The enzymes, including human estrogen sulfotransferase (hEST) and hydroxysteroid sulfotransferase (hHST), are generally homodimers in solution with mouse estrogen sulfotransferase (mEST) being one of few exceptions. To identify the amino acid residues responsible for the dimerization, eight residues on the surface of hEST were...
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