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Article

Sulfatases and human disease.

Annual review of genomics and human genetics - 1 Jan 2005

Diez-Roux Graciana, Ballabio Andrea

Abstract excerpt

Sulfatases are a highly conserved family of proteins that cleave sulfate esters from a wide range of substrates. The importance of sulfatases in human metabolism is underscored by the presence of at least eight human monogenic diseases caused by the deficiency of individual sulfatases. Sulfatase activity requires a unique posttranslational modification, which is impaired in patients with multiple sulfatase...

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Source

Identifiers

PMID: 16124866
DOI: 10.1146/annurev.genom.6.080604.162334

Genes

SUMF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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