Article

Design, Synthesis, and Efficacy of Novel Trojan Horse Compounds Targeting Metabolic Vulnerabilities in Prostate Cancer

2024-08-30

Abstract excerpt

<h4>Background and purpose</h4> Prostate cancer (PCa) remains a significant global health concern, warranting the development of new therapeutic strategies. 1 Metabolic reprogramming, an emerging hallmark of PCa progression characterized by aberrant nutrient utilization, has become a focus area in developing new treatments. Among these metabolic alterations, the Warburg effect—a shift towards aerobic glycolysis—...

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Literature Corpus work: cc44a020-5523-5115-b0d4-f2fd70281db2
DOI: 10.1101/2024.08.29.610353

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