Article

Context dependency of nucleotide probabilities and variants in human DNA

2021-07-23

Abstract excerpt

<h4>Background</h4> Genomic DNA has been shaped by mutational processes through evolution. The cellular machinery for error correction and repair has left its marks in the nucleotide composition along with structural and functional constraints. Therefore, the probability of observing a base in a certain position in the human genome is highly context-dependent. <h4>Results</h4> Here we develop context-dependent n...

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Literature Corpus work: cc3f871f-f76f-53d9-9b86-2a81cd539bcb
DOI: 10.1101/2021.07.22.453351

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